The video shows the lineage progression of the aNSC (black arrow) depicted in Fig. 5a,c of the protocol below. The left panel shows the sequence of phase contrast images and the right panel the corresponding development of the lineage trees. Note the generation of both neuronal and astroglial progeny, as indicated by the final image following post-imaging immunocytochemistry. Full protocol described in: Ortega, F., Costa, MR, Simon-Ebert, T., Schroeder, T., Götz, M. & Berninger, B. Using an adherent cell culture of the mouse subependymal zone to study the behavior of adult neural stem cells on a single-cell level. Nature Protocols 6, 1847–1859 (2011) doi: 10.1038/nprot.2011.404 dx.doi.org

Cell biologist Dr Mirella Dottori and neuroscientist Dr Alice Pébay discuss how their work with induced pluripotent stem (IPS) cells, aka adult stem cells, may hold the key to a cure for Friedreich’s ataxia and other genetically transmitted diseases. They also explain how adult stem cells differ from embryonic stem cells. With science host Dr Shane Huntington.

Neural Stem Cells for Brain and Spinal Cord Repair (Contemporary Neuroscience)

Univ. of South Florida, Tampa. Provides an overview of the biological properties and functional characteristics of neural stem cells, and areas where cells may soon be helpful. Features clinical properties of NCSs, practical guidance, and applications. DNLM: Central Nervous Diseases–therapy.

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