Olga Momcilovic speaks at the 2011 CIRM Grantee Meeting about the use of induced pluripotent stem (iPS) cells to better understand the causes of Parkinson’s and to develop therapies. Momcilovic is a CIRM Scholar and postdoctoral research fellow at the Buck Institute located in Novato, California.
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This volume is a compendium of cutting-edge molecular methods for the successful transplantation of hematopoietic stem cells. The contributors are world-renown leaders in the field. They describe promising tools for stem cell transplant research models, such as in vivo bioluminescence imaging. They discuss HLA typing, PCR-SSP typing, and HLA antigens. This volume is an invaluable source for biochemists, molecular biologists, and clinicians.
This lecture by Dr. Nadia Rosenthal discusses the importance of adult stem cells in the tissue maintenance, development and regeneration. Part 2 of 6. HHMI description: Mature organisms have stem cells of various sorts, called adult stem cells. Adult stem cells supply cells that compensate for the loss of cells from normal cell death and turnover, such as the ever-dying cells of our skin, our blood, and the lining of our gut. They are also an essential source of cells for healing and regeneration in response to injury. Some animals, such as sea stars, newts, and flatworms, are capable of dramatic feats of regeneration, producing replacement limbs, eyes, or most of a body. It is an evolutionary puzzle why mammals have more limited powers of regeneration. Researchers are interested in pinpointing where adult stem cells reside and in understanding how flexible adult stem cells are in their ability to produce divergent cells such as muscle and red blood cells. Understanding the sources and the rules for the differentiation of adult stem cells is essential for tapping their therapeutic potential. Since consenting adults can provide adult stem cells, some people think that adult stem cells may be a less controversial area of research than embryonic stem cells.
CIRM has funded the Diabetes Disease Team led by scientists at ViaCyte, Inc., UCSF, and the La Jolla Institute for Allergy and Immunology. This team aims to bring an embryonic stem cell based therapy for diabetes to clinical trials. For more info, see our diabetes fact sheet: www.cirm.ca.gov
A company is locked in a battle with the FDA over the use one’s own stem cells. The company argues that one has the right to over one’s own body? If that’s true, why is the FDA blocking this treatment? Find out. Plus, doctors are refusing to treat children that do not get vaccinated. Is this ethical? See more at www.pjtv.com
When Barry Goudy found out he had multiple sclerosis he feared the worst. Doctors told him he might lose his eye sight and the ability to walk. As a very active husband, father and hockey coach, Barry couldn’t think of anything worse than losing his ability to get around. But then he learned of a new way to treat MS with a stem cell transplant. The transplant worked and today he’s living proof of the miracles that can come from Adult Stem Cell Research.
Tim has Cerebral Palsy (CP) and came to Dr. Steenblock in Mission Viejo, CA for stem cell therapies. You can watch his video to see how stem cells helped him. For more videos on Cerebral Palsy & Stem Cells, please visit our sites: www.cerebralpalsycure.com http www.strokedoctor.com http www.davidsteenblock.com http
This lecture, by Dr. Nadia Rosenthal, discusses the role of stem cells in the regeneration and repair of tissues, and their possible medicinal application through the harnessing of their regenerative properties. HHMI description: Human tissues vary in their ability to heal and regenerate. The nervous system has weak powers of regeneration, while the skin is quick to make new cells for repair. Mammalian muscle cells are intermediate in their ability to regenerate. Human muscle can regenerate in response to minor wounds and normal wear and tear, but humans will not grow a new bicep, for example, in response to amputation. The heart is the most important muscle in the body and yet has feeble regenerative capabilities. Research into the wholesale production of new replacement organs and limbs is in its infancy, but research into enhancing normal levels of regeneration is progressing rapidly. Recent discoveries concerning the location and characteristics of adult stem cells and the signals that wounded tissue produces to activate stem cells have increased our understanding of regeneration. Insulin-like growth factor 1 (IGF1) is an example of an important stem cell communication molecule. If the activity of the growth factor is experimentally enhanced, muscle regeneration improves.
This clip is based on an interview with Gabi and follows him through his daily physical therapy routine in Qingdao, China. He discusses receiving umbilical cord stem cells in China for his spinal cord injury and the hope he holds for others with similar injuries.
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Citation Details Title: All Tissues May Have the Potential To Produce Stem Cells. Author: Ti
This lecture, by Dr. Nadia Rosenthal, discusses the role of stem cells in the regeneration and repair of tissues, and their possible medicinal application through the harnessing of their regenerative properties. HHMI description: Human tissues vary in their ability to heal and regenerate. The nervous system has weak powers of regeneration, while the skin is quick to make new cells for repair. Mammalian muscle cells are intermediate in their ability to regenerate. Human muscle can regenerate in response to minor wounds and normal wear and tear, but humans will not grow a new bicep, for example, in response to amputation. The heart is the most important muscle in the body and yet has feeble regenerative capabilities. Research into the wholesale production of new replacement organs and limbs is in its infancy, but research into enhancing normal levels of regeneration is progressing rapidly. Recent discoveries concerning the location and characteristics of adult stem cells and the signals that wounded tissue produces to activate stem cells have increased our understanding of regeneration. Insulin-like growth factor 1 (IGF1) is an example of an important stem cell communication molecule. If the activity of the growth factor is experimentally enhanced, muscle regeneration improves.
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